Neutrophils tether to TNFα-treated endothelium, roll (A), and adhere (B). The tethering and rolling was entirely inhibited by an E-selectin/L-selectin antibody (EL-246; A). The anti-CD18 antibody (IB₄ ) inhibited neutrophil adhesion (B) without inhibiting rolling (data not shown). (▪) Without antibody; (▵) with antibody. *P < .05 relative to untreated neutrophils.