Fig. 5.
In the presence of antiselectin antibody (EL-246), DHCB-treated neutrophils did not roll or adhere to TNFα-treated endothelium at 2 dyne/cm2. Shear was decreased at 2-minute intervals and neutrophil tethering and adhesion was examined in the (▵) presence and (▪) absence of the anti–α4 -integrin antibody, HP2/1. It should be noted that rolling was not observed in this series of experiments. *P < .05 relative to the no antibody condition.