Effect of anti-CD2 MoAb on primary lymphocytes activated with anti-CD3 MoAb. Anti-CD3 (1 μg/well) and/or anti-CD2 MoAb (1 μg/well) were allowed to adhere in 96-well flat-bottomed plates as described above. T lymphocytes (2 × 10⁵/well) were cultured for different times on coated plates in the presence of 100 U/mL IL-2. Results are expressed as (A) the percentage of apoptosis (broad hypodiploid peak), (B) the median of Fas expression, or (C) the percentage of Fas-L⁺ cells and are the mean of three separate experiments. The standard errors (<10%) are omitted for clarity. *P < .01, significant inhibition comparing anti-CD3 + anti-CD2–treated with anti-CD3–treated group.