Fig. 6.
![Fig. 6. Effect of ADP addition on collagen plus thrombin-induced platelet prothrombinase and [Ca2+]i . Prothrombinase activity (top, A and B), and average [Ca2+]i (bottom, C and D) in platelets stimulated by collagen plus thrombin in the presence and absence of stirring, with 5 μmol/L ADP (+ADP) or elution buffer (−ADP) added 30 seconds after stimulation. Results (mean ± SE) are shown for five normal subjects (N) and seven δ-SPD-HPS patients. P values: **<.01, ***<.001.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/89/5/10.1182_blood.v89.5.1599/3/bl_0049f6.jpeg?Expires=1735832741&Signature=I5NlQEAOQ7QyKPEtXXS4iiibcf7rc6IsUPR6t~yMX7vvuGiAzBWubFA7AkD1IasjWRWu2WXpiaAnE6lrUswsArfdh1rBAOdeIF~e89PNwYwD9Rof8RNRKMUwz9FQIH~7yPOVsJe6Q0ZD-WOMNyf4fMDgUaW8HlFtMvHz4mV8T4Bg-siwDoZtyfsfq8oiyzqIq2Dn3HD-0CoTxFJlRGCwn7sKpeSfgih714n-~8gPoixpdDW5DsUeCRi7P~zL915ktlKdDDIzkXNqb--xcqeyOWxFclWCtRdMcGeNyjfYYlpHI~4CAJ0qu5JCAqgWO7M~bPz0XpRZWobUPs9xEteNAg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of ADP addition on collagen plus thrombin-induced platelet prothrombinase and [Ca2+]i . Prothrombinase activity (top, A and B), and average [Ca2+]i (bottom, C and D) in platelets stimulated by collagen plus thrombin in the presence and absence of stirring, with 5 μmol/L ADP (+ADP) or elution buffer (−ADP) added 30 seconds after stimulation. Results (mean ± SE) are shown for five normal subjects (N) and seven δ-SPD-HPS patients. P values: **<.01, ***<.001.
