Regulation of Bcl-2 and Bax in wt-p53⁺ ALL lines either sensitive (Sup-B13 and Sup-B15) or resistant (UoC-B1 and Reh) to IR (10 Gy). (A) shows Western blot analysis of Bcl-2 and Bax protein that was extracted either pre-IR (C) or at 7 hours post-IR (IR). Densitometric scan of bands in (A) shows relative levels of protein post-IR compared with pre-IR (B).