Fig. 4.
Fig. 4. Combinations of three cytokines can selectively promote DNA synthesis by GC B cells. Paired GC B cells (A) and resting B cells (B) were cultured for 6 days with CD40 MoAb, G28-5 in the presence of CD32-L cells and various combinations of three cytokines after which [3H]thymidine uptake was measured. These cytokine combinations acted synergistically in promoting DNA synthesis by GC B cells (see Results). Data are mean cpm ± SD for three to five experiments.

Combinations of three cytokines can selectively promote DNA synthesis by GC B cells. Paired GC B cells (A) and resting B cells (B) were cultured for 6 days with CD40 MoAb, G28-5 in the presence of CD32-L cells and various combinations of three cytokines after which [3H]thymidine uptake was measured. These cytokine combinations acted synergistically in promoting DNA synthesis by GC B cells (see Results). Data are mean cpm ± SD for three to five experiments.

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