Fig. 4.
Effect of O6-benzylguanine pretreatment on the induction of micronuclei in mouse bone marrow following the administration of various doses of temozolomide (A) and BCNU (B). Results are presented as mean ± SE from four mice per group. The level of significance in the presence and absence of O6-BeG is expressed as *P < .05 and ***P < .001 as assessed by unpaired Student's t-test. (□), Control; (▨), O6-BeG.