Fig. 3.
Composite photograph showing the cytologic features of MCL. (A) Typical cytology of MCL characterized by cells with small, slightly irregular nuclei, inconspicuous nucleoli, and minimal cytoplasm. Note the frequent epithelioid histiocytes (arrows). (B) MCL with prominent features of transformation, but not clearly blastic. Increased numbers of larger cells with fine chromatin and inconspicuous nucleoli are shown (arrows). (C) Blastic MCL. Note the cytologic resemblance to lymphoblastic lymphoma. (D) OS of 80 patients with MCL based on the presence of blastic features. The 5 cases designated as blastic MCL were associated with a significantly shorter survival when compared with that of all others (n = 75) including those with features of transformation as shown in (B).