Fig. 4.
Genomic organization of the Ig heavy chain gene in bcr-ABL chimeric mice. DNA was obtained from control and bcr-ABL chimeric tissues, digested with BamHI, and fractionated into 1% agarose gel. Specific rearrangement was detected by Southern blot analysis with an Ig heavy chain specific probe in bcr-ABL chimeric tissues. PB, peripheral blood; BM, bone marrow.