Fig. 6.
Addition of F(ab)2 fragments of anti-CD44 MoAbs or soluble CD44 Rg blocks proliferation of spleen cells stimulated with HA. Spleen cells were incubated with medium (control) or stimulated with HA (A) in the presence of soluble CD44 Rg or human IgG or (B) in the presence of F(ab)2 fragments of anti-CD44 MoAbs alone (diluted 1:10, 1:50, 1:100 of hybridoma supernatants). Cell proliferation was measured as described in the legend to Fig 1. Bars with an asterix indicate statistically significant decrease when compared with the controls.
