Specific activation of anti-HIV CTL in patients no. 1 (A) and 2 (B) by vCP205 (Env and Gag) and vCP300 (Env, Gag, Pol, and Nef ) ALVAC vectors. Data are reported as the percentage of specific lysis at an E:T = 10:1, subtracting the background against vaccinia-infected autologous BLCL. CD4- or CD8-depleted effector populations were obtained according to the procedure described in the Materials and Methods. (□) vCP205; (▪) vCP300.