Fig. 4.
Immuno-EM of RBC membrane skeletons using the surface replica method with antihuman spectrin rabbit polyclonal IgG antibody. Aggregated spectrin was noted in the 4.1 (−) Madrid case ([B] n = 1, obs 12) as compared with normal subjects ([A] n = 20, obs 52). Original magnification × 100,000. Bars indicate 0.1 μm.