Fig. 3.
Results of FISH analysis performed on the NALM-6 cell line with 5q ([A], y773D3; [C], cCML182; [E], y756A2) and 12p ([B],c106B9; [D], b204K22; [F], c214F3) derived probes. Note the presence of hybridization signals on the normal chromosomes 5 or 12 only with, respectively, cCML182 and b204K22. The signals of the centromeric chromosome 12 probe (pBR12, D12Z3) are shown in red, the signals of the cosmid, YAC, and BAC clones are shown in yellow. The arrowheads indicate the der(5) and the der(12).