Effect of MoAb 9 to vWF blocking the αvβ3-dependent endothelial adhesion to vWF. Nonstimulated endothelial cells were incubated with increasing concentrations of MoAb 9 before adhesion to WT-rvWF (•), RGGS-rvWF (▴), or to ΔA1-rvWF (▪). Adhesion was measured as described in the legend to Fig 1. MoAb 9 inhibits adhesion to WT-rvWF to the same extent as adhesion to ΔA1-rvWF. Of note is that adhesion to RGGS-rvWF is also inhibited by MoAb 9.