American Society of Hematology

Fig. 2.

$Fig. 2. Growth of myeloid (CFU-GM) and erythroid (BFU-E) progenitor cells from BM CD34+, CD34+Rhodamine 123 dull, CD34+ Rhodamine 123 bright, and CD34+ cells following 4-HC treatment. The different cell populations were cultured in either 6 HGF or 6 HGF + FLT3L (shown in the solid bars) and colonies scored at day 14. The mean and standard error from triplicate plates from a single representative experiment are shown. CFU-GM and BFU-E numbers refer to the number of colonies grown from 1,000 cells with the respective phenotypes. The number of CFU-GM in the total CD34+ fraction, the CD34+ Rhodamine dull and the 4-HC–treated CD34+ cells was significantly greater (as indicated by the *) when cultured with 6 HGF + FLT3L (P = .05, .06, and .05, respectively) than with 6 HGF.$

Growth of myeloid (CFU-GM) and erythroid (BFU-E) progenitor cells from BM CD34⁺, CD34⁺Rhodamine 123 dull, CD34⁺ Rhodamine 123 bright, and CD34⁺ cells following 4-HC treatment. The different cell populations were cultured in either 6 HGF or 6 HGF + FLT3L (shown in the solid bars) and colonies scored at day 14. The mean and standard error from triplicate plates from a single representative experiment are shown. CFU-GM and BFU-E numbers refer to the number of colonies grown from 1,000 cells with the respective phenotypes. The number of CFU-GM in the total CD34⁺ fraction, the CD34⁺ Rhodamine dull and the 4-HC–treated CD34⁺ cells was significantly greater (as indicated by the *) when cultured with 6 HGF + FLT3L (P = .05, .06, and .05, respectively) than with 6 HGF.

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