Effect of rD-mPGPtide on BM engraftment. CFU-GM assays were performed on day 5 post-BMT in the haploidentical (A) and the class II-disparate (B) strain combinations. Spleen cells were pooled from three donor mice per group, plated in triplicate in semisolid methylcellulose media, and cultured for 6 days. Colonies containing more than 30 (CFU-GM) cells were scored as positive. The results are from one experiment representative of three separate experiments. Values are the percent increase CFU-GM from anti-CD4 MoAb and rD-mPGPtide–treated mice over the PBS control, which provided the baseline level.