Fig. 5.
Dose-dependent induction of CD95 expression on CD34+ cells derived from BM of CML patients. Total BM cells were cultured in the presence of various concentrations of IFN-α for 48 hours, and stained with PE-conjugated CD34 and FITC-conjugated CD95 MoAb. Statistical analysis (paired t test): control v 500 and 1,000 U/mL IFN-α; P < .05 (summary of 7 experiments).