Fig. 8.
Inositol-5-phosphatase activity of pp135. The lysates from UT-7 cells with (+) or without (−) GM-CSF stimulation were mixed with normal rabbit serum (NRS), anti-P6, or anti-Shc. The inositol-5-phosphatase activity of the resulting immunoprecipitates was measured using [3H]inositol (1,3,4,5)-P4 as the substrate. Results are expressed as picomoles of hydrolysis product per 15 minutes.