IUT patients (IUT) and donors that were HLA-DR matched with these patients (PBL) were used as responders (resp ) in the PLT. The original IUT donors and third-party individuals that were HLA-DR matched (3dp matched) and completely mismatched (3dp mm) with the original IUT donors were used as stimulators (stim ). HLA-DR typing: Fetus 1. DR 1, 16(2); PBL, DR 1, 15(2); IUT donor, 1 •. DR 1, 2 ○. DR11 (5), 4*. DR 3, 4; 3dp matched, 2 ○. DR 5, 4*. DR 3, 4; 3dp mm, • DR 6, 8. Fetus 2. DR 1, 7; PBL, DR 1, 7; IUT donor, 1 ▾. DR 1, 2 ▵. DR 11(5), 3 ▿. DR 6, 8; 3 dp matched, 2 ▵. DR 5, 3 ▿. DR 6, 8; 3dp mm, ▾ DR 3, 4. Fetus 3. DR 1, 4; PBL, DR 1, 4; IUT donor, 1 ▪. DR 6, 7, 2 □. DR 2, 4; 3dp matched, 1 ▪. DR 6, 7, 2 □. DR 2, 4; 3dp mm, ▪ DR 3, 8.