Fig. 4.
Granulocyte-macrophage (A), BFU-E (B), and megakaryocyte progenitors (C) from bone marrow of IL11Ra −/− mice. Mean of total colony numbers ± standard deviations (n = 7 for each genotype, for [A] and [B]) in replicate cultures containing 50,000 bone marrow cells stimulated with final concentrations of GM-CSF at 10 ng/mL, IL-3 at 10 ng/mL, SCF at 100 ng/mL, MGDF at 200 ng/mL, EPO at 2 U/mL, IL-6 at 100 ng/mL, and G-CSF at 10 ng/mL. Acetylcholine esterase-stained megakaryocyte progenitors (n = 4 for each genotype) are expressed as a percentage.