Disease-free survival of the filgrastim (n = 178) and of the placebo group (n = 177). After a median follow-up of 24 months the median disease-free survival was 10.1 months for the filgrastim group and 9.4 months for the placebo group with a probability of disease-free survival at 3 years of 20% in the filgrastim versus 21% in the placebo group.