Effect of p53 on stimulation of different cellular gene promoters by Tax. Jurkat cells were cotransfected with the promoter-CAT constructs indicated (10 μg) and 5 μg Tax expression vector (BC3.9 Sph) or the parental vector (BC12), together with expression vectors for wild-type p53, mutant p53s (143A, 248W, and 273H), or parental vector pCMV-NeoBam (5 μg). (▪) − Tax; (▨) + Tax.