Involvement of TNFRs in the TNF-induced enhancement of memory and naive B-cell locomotion. Freshly purified memory (A) and naive (B) B cells were treated with anti-TNFR I, anti-TNFR II, or with an isotype-matched MoAb of irrelevant specificity (control MoAb). Cells were subsequently tested in locomotor assays in the absence (Nil) or in the presence of 1 ng/mL rTNF. Results are means ± SE from six to seven different experiments. *P < .05, **P < .005, versus isotype-matched MoAb and rTNF-treated control, nonparametric Mann-Whitney U-test.