Fig. 2.
Bryo-1 synergizes with IL-2 in triggering cytokine secretion from monocytes. Cells were stimulated for 18 hours with medium alone (▪) or supplemented with IL-2 (1,000 U/mL) (▧) in the presence or absence of increasing concentration of bryo-1. Supernatants were harvested and assayed for secreted IL-1β, IL-6, TNF-α, and IL-8 by specific ELISA. Results from one representative experiment, expressed as ng/mL per 2 × 106 cells/mL, are shown.
