Bryo-1 differentially affects IL-2– and IFN-γ–dependent secretion of IL-1β and TNF-α. Monocytes were stimulated with IL-2 (1,000 U/mL) or IFNγ (500 U/mL) in the presence or absence of 0.1 ng/mL of bryo-1. Supernatants were collected after 18 hours of treatment and assayed for IL-1β and TNF-α by ELISA. Data from one representative experiment are shown.