Fig. 4.
Northern blot analysis of the CEV14-PDGFRβ transcript. The PDGFRβ probe P2, located 3′ of the translocation breakpoint, detects wild-type 5.7-kb and 4.8-kb PDGFRβ transcripts in human BM stroma (HBS), while a novel 10-kb transcript is seen in the patient's leukemia cells with the t(5; 14) translocation. CEV14 probe C1 detects the same 10-kb transcript and one of the major CEV14 transcripts, while 10.5-kb, 9.0-kb, and 7.0-kb CEV14-specific transcripts are expressed in MEG-A2 cells.