Fig. 4.
Nucleotide sequences of MPO exon 9-10 clones (A and C) and of cDNA clones from the MPO-deficient subject MP (B and D). (A) < include the 14-base deletion, whose sequence is reported. (B) Δ77 shows the position of the 77-base deletion. (C) Upper case, exon 9 and exon 10. Lower case, intron IX; 1 — normal sequence, 2 — 14-base deleted sequence. (D) Nucleotide and deduced aminoacidic sequences of normal allele (1) and of 77-base deleted allele (2). Dots, deleted bases, or deleted amino acids.