Deduced amino acid sequences of the VH regions of tumor cells from patients with mantle cell lymphoma. Comparisons are made with the best aligned germline VH genes. The first five patients had VH regions identical to (=) germline VH genes. In the latter five cases, the best aligned germline VH genes are fully shown. Dots indicate alignment between the patient VH region and the germline VH gene. Exchange mutations are indicated by the letter of the derived amino acid. Replacement mutations shown in uppercase and silent mutations in lowercase. The CDR regions are underlined. Germline (GL) VH gene sequences derived from the data-bases as shown: GL1 = EMB‖X92278‖HSIGVH5. GL2 = EMB‖Z14237‖HSVH433G. GL3 + 4 = GB‖L10090‖HUMIGHCAC. GL5 = GB‖M99406‖HUM10IGVH. GL6 = EMB‖X92278‖HSIGVH5. GL7 = GB‖UO3893‖HSU03893. GL8 = GB‖L06618‖HUMIGHHVAAE. GL9 = GB‖L10094‖HUMIGHCAG. GL10 = GB‖L10088‖HUMIGHCAA.