Sequence and location of band 3 peptides. The membrane domain of the band 3 monomer is depicted as 14 transbilayer helices connected by loop sequences. The position and sequence of peptides 2f (residues 476-485) from extracellular loop 2 connecting helices 3 and 4, and 3d (residues 547-553) from extracellular loop 3 connecting helices 5 and 6, are shown. Extracellular loop 7, the putative position of peptide 7e (residues 814-820: KPPKYHP), is also indicated.