(A) Priming of murine BMMC with KL before triggering with IgE + antigen. IgE-sensitized BMMC were primed for 5 minutes with control diluent or KL (100 ng/mL) and then activated with TNP-BSA. Data are expressed as the percentage of release of hexoseaminidase of two replicate points. (B) Dose-response of KL-CD ( — )and KL-NC (- - -) priming of BMMC activation. Data are expressed as a percentage of the maximal response achievable over the baseline. The baseline level of activation was 20.6% with IgE + antigen (TNP-BSA) alone and the maximal level of activation was 57.2% with KL + IgE + antigen. The data represent the mean of two points from one of three representative experiments.