Radiologic evolution in patient B. (A) Postcontrast abdominal CT scan on February 10, 1994 shows multiple small hypodense areas in all segments of the liver suggestive of hepatic candidiasis. Twenty-four days previously, the patient had recovered from severe neutropenia after the second cycle of chemotherapy for ALL. (B) On May 4, 16 days after the neutrophil count had dropped below 500/μL in the third chemotherapy cycle, there is clear improvement of the radiologic findings, with only a few hypodense areas in the liver.

(C) On June 6, 31 days after normalization of neutrophils, CT again shows multiple lesions in the liver (arrowheads) with a different presentation: the small lesions show strong peripheral enhancement. (D) On September 2, 129 days after neutrophil recovery, all hepatic lesions have completely resolved.