ICSBP-transcript numbers in peripheral blood from normal healthy individuals and patients with different kinds of leukemias. (A) Lack of ICSBP-transcript numbers in CML-patients was detected by a semi-quantitative RT-PCR assay. Comparison of three healthy normal blood donors (NB; lanes 1 through 3) with four CML patients at diagnosis (CML; lanes 4 through 7) and three hydroxyurea-treated CML patients (CML, lanes 8 through 10). The expression level is displayed as integrated optical density (IntOD). (B) As (A), except that ICSBP-transcript numbers of 33 normal healthy blood donors, 34 CML, 32 AML, 11 CLL, 11 ALL, and 6 CMMoL patients were compared.