ICSBP-transcript numbers in CD19⁺ B cells from normal healthy individuals and CML patients. High transcript levels were detected in cells from normal individuals (lanes 1 through 7), low levels in two of three CML patients without IFN-α (lanes 8 through 10) whereas another patient with high ICSBP levels had received IFN-α before (lane 11; IFN-α was withdrawn 6 months before sample was taken). One of two CML patients still under IFN-α exhibited low, the other high ICSBP levels (lanes 12 and 13). The mean of three experiments is displayed (±SEM).