Effect of SDZ MRL 953 on serum levels of G-CSF and white blood cell counts in cancer patients. (A) Mean values of G-CSF serum concentrations in patients after the first of seven injections of (▿) vehicle control (n = 5) or SDZ MRL 953, subdivided into three dose groups: (♦) 18.0 μg/kg (n = 3), (⋄) 23.4 and 28.8 μg/kg (n = 6), and (•) 34.2 and 39.6 μg/kg (n = 6). Statistics of the highest dose group are included in the text. (B) Mean values of white blood cells, specified in neutrophil granulocytes (solid box), lymphocytes (single dashed box), monocytes (open box), and other leukocytes (double-dashed box), in patients after the first of seven injections of SDZ MRL 953 (34.2 and 39.6 μg/kg, n = 6).