Fig. 4.
Histologic findings of RPMI 8226 tumors at day 25 after tumor inoculation. The subcutaneous tumors in SCID mice were removed 3 days after injection (100 μg/mouse) of (A) control IgG or (B) anti-HM1.24 MoAb. Necrotic areas and infiltrating cells were seen in the tumor from mice treated with anti-HM1.24 MoAb. Stained with hematoxylin and eosin. Original magnification ×130.