Analysis of the patient's β3 gene. (A) SSCP analysis of β3 exon 4 in a normal control (lane 1), four unrelated thrombasthenic patients (lanes 2, 3, 5, and 6), and the patient (lane 4). The patient's lower band migrated faster than any of the other studied samples. (B) Sequence analysis of wild-type (WT) and the patient's (MK) DNA for β3 exon 4 showing a single T → G substitution in this exon.