Western blot analysis of cell lysates (B-LCLs) from WAS patients (see Table 1 for detailed description of the mutations). (A) Blots from patients with nonsense mutations or missense mutations affecting exons 1 to 4. (B) Blots from patients with splice-site mutations, insertions, or deletions located in exons 7 to 11 (except patient SD, who has a splice-site mutation affecting intron 3).