Fig. 6.
MMP-1 production in coculture experiments. Stromal cells were seeded in 96-well plates (Costar) at a concentration of 1.5 × 104 cells/100 μL/well. Myeloma cells (1.25 × 105 cells/well) were added to stromal cells, and supernatants were harvested after 48 hours of coculture. MMP-1 level was evaluated by an ELISA. Five differents experiments are shown.