Fig. 7.
Effects of activation inhibitors on Ca2+ responses and annexin V binding capacity of platelets adhering to collagen. Fura-2–loaded platelets were treated with various drugs and allowed to adhere to collagen in the presence of 2 mmol/L CaCl2 and FITC-annexin V, exactly as described for Fig 6. Given are the percentages of platelets that were elevated in [Ca2+]i (A), and stained positively with FITC-annexin V (B) after 15 minutes of adhesion. Data are averaged values ± SEM from three to five independent experiments (350 to 600 cells).