Effects of HIV-1 infection on growth of human LTBMC. (A) Growth curves of HIV-1–infected and –uninfected LTBMC. The total number of cells present in duplicate LTBMC are depicted. (○) Represent the cell numbers for the HIV-1–infected culture, (•) represent the cell numbers for the uninfected culture. (B) Numbers of cells in HIV-1–infected and –uninfected LTBMC. The total numbers of cells present in LTBMC cultured on nontransduced, primary human stroma 3 weeks after infection with HIV-1 (□) or uninfected (▪) were counted. The figure shows results from three independent experiments. (C) Numbers of CFU in HIV-1–infected and –uninfected LTBMC. The total numbers of clonogenic CFU progenitors from the same three sets of LTBMC depicted in (B) were assayed 3 weeks after infection with HIV-1 (□) or uninfected (▪).