Effects of HIV-1 infection on growth of human LTBMC. (A) Numbers of cells in HIV-1–infected and –uninfected LTBMC. The total numbers of cells present in LTBMC were counted 3 weeks after infection with HIV-1 (□) or uninfected (▨) cultured on: human stroma transduced with the LN vector (LN-stroma), human stroma transduced with the L-RRE-neo vector (L-RRE-Neo-stroma), the murine S17 stromal line (S17), or without any stromal layer (no stroma). The figure shows results from three independent experiments (error bars represent the SEM). (B) Numbers of CFU in HIV-1–infected and –uninfected LTBMC. The total numbers of clonogenic CFU progenitors from the same three sets of LTBMC depicted in (B) were assayed 3 weeks after infection with HIV-1 (□) or uninfected (▨).