Fig. 4.
Time-dependent effects of Lp(a) at 100 μg/mL (▪) and 300 μg/mL (•) on cGMP formation by human peripheral monocytes incubated at 37°C in HBSS at a density of 107 cells/mL. The incubations were stopped by addition of perchloric acid and rapid cooling. After neutralization, cGMP contents were determined radioimmunologically. *P < .05 and **P < .01 versus basal values at time point 0 minutes. The data show mean ± SEM for four independent experiments.