Electron micrograph of a frozen thin section of myelocytes immunolabeled for LAMP-2. In (a), large vesicles (V) and the MLC are labeled with GAM-10 (arrowheads). Note the absence of labeling in large Ag as well as in the Sg and PM. In inset, higher magnification of another multilaminar compartment positive for LAMP-2. (b) Two organelles contain label (arrowheads). The typical MVB are labeled for LAMP-2 as is the MLC. The membranes of the small granules (Sg) are not labeled nor is the Gc. Nucleus (Nu).