Immunohistochemistry of CD3 in case 1: (A) low (40×), (B) high (400×). CD3⁺ T cells are associated with clusters of H-RS cells, often forming a ring around the H-RS cells. Inset shows CD30⁺ H-RS cells. Immunohistochemistry of MB2 in case 2: (C) low (40×), (D) high (400×). MB2⁺ CLL cells are present around a nodule of HD. H-RS cells are admixed with T cells and histiocytes and only scattered MB2⁺ small lymphocytes are present.