Fig. 2.
ALLN, PDTC, or NaSal, but not dexamethasone, decreases OSM-induced expression of P-selectin mRNA in HUVEC. The experiment was performed exactly as in Fig 1A and B, except that the cells were incubated for 20 hours in the presence or absence of 10 ng/mL of OSM. The data are representative of two experiments. The data in panel B were also pooled with the results from the other experiment. Statistical analysis of the pooled results revealed that ALLN, PDTC, or NaSal significantly decreased OSM-induced P-selectin mRNA levels (P ≤ .05).