A schematic representation of full-length or mutant AML1, AML1/ETO(MTG8), and AML1/Evi-1. The runt domain and the PST region (see text) of AML1 (also called AML1b) are shown by striped and dotted boxes, respectively. Other regions of AML1/ETO(MTG8) (proline-rich regions and the zinc finger domain) and AML1/Evi-1 (the noncoding exon of Evi-1, zinc finger domains and the acidic domain) are indicated.