Appearance of F4/80-positive cells in fetal and neonatal spleen. Tissues were stained, positive cells were quantified, and results are expressed for +/csfm^op (•) andcsfm^op/csfm^op (▴) offspring after matings of (A) +/csfm^op female ×csfm^op/csfm^op male and (B)csfm^op/csfm^op female ×+/csfm^op male mice as in Fig 2. Where indicated,+/csfm^op differed fromcsfm^op/csfm^op at #P < .01 and *P < .001, respectively. Results of multiple comparisons over time, where indicated, showed ^aP < .025,^bP < .01, and ^cP < .001 versus day13; ^dP = .08, ^eP< .05, ^fP < .025, ^gP < .01, ^hP < .005, and ⁱP < .001 versus day 15; ^jP < .01 and^kP < .001 versus day 18; ^lP < .05, ^mP < .025, and ⁿP < .001 versus postnatal day 1; and ^oP < .005 versus postnatal day 4, respectively.