Fig. 2.
In vivo distribution of 125I-rTpo within the blood and spleen of NF-E2 knockout (KO) and wild-type (WT) mice. (A) Platelet levels (thousands per microliter) measured before injection. Mice were injected intravenously with 125I-rTpo and killed 3 hours later, and radioactivity associated with the plasma fraction (B), blood cells (C), and spleen (D) was measured. Data are presented as the mean ± SD from two separate experiments. BCA, blood cell–associated.