Cytotoxic activity of T-cell lines and clones against autologous monocytes pulsed with peptide. Monocytes pulsed with either a bcr-abl–derived peptide (P2, P3, or P4) or the melanoma peptide Mart-1 were used as targets for the cell lines P21 and M81 (generated against bcr-abl and Mart-1 respectively) and cell clones P210 and P218 derived from P21. Data shown represents the mean ± SD percent specific lysis in chromium release assays performed in triplicate with an E:T ratio of 10:1. *Significant lysis (P < .0002).