Fig. 1.
Partial karyotypes from six different patients showing examples of recurring 1q aberrations seen in MM. Patient No.14 showing normal chromosomes 1 on left and der(15)t(1;15)(q10;q10) on right (A). Patient No. 7 showing normal chromosomes 1 on left and der(12)t(1;12)(q10;q24) on right (B). Patient No. 4 showing normal chromosomes 1 on left, der(8)t(1;8)(q10;p23) in middle, and der(16)t(1;16)(q10;p10) on right (C). Patient No. 1 showing two normal chromosomes 1 and an extra copy of 1q on left, a der(5)t(1;5)(q10;q15) in the middle, and der(16)t(1;16)(q10;p13) on right (D). Patient No. 2 showing der(5)t(1;5)(q10;q15) in middle and der(17)t(1;17)(q10;q25) on right (E). Patient No. 21 showing three chromosomes 1 on left with three normal copies of chromosome 19 and a der(19)t(1;19)(q10;p13) on right (F). Arrows indicate chromosome fusion points.